Best Price Right Now
Best moneyline: New England Patriots +275 at BetMGM (runner-up +265 at FanDuel); Buffalo Bills -300 at LowVig.ag (runner-up -300 at BetOnline.ag).
Spread: Buffalo Bills -7 (consensus). Best price: New England Patriots +7 (-110) at MyBookie.ag (runner-up -112 at Pinnacle); Buffalo Bills -7 (+105) at LowVig.ag (runner-up +100 at BetUS).
Total (over/under): 48.5 (consensus). Best price: Over 48.5 (-105) at Fliff (runner-up -107 at LowVig.ag); Under 48.5 (-107) at LowVig.ag (runner-up -107 at Pinnacle).
Compared across 19 sportsbooks as of September 28, 2026 at 9:00 AM UTC. The best book often differs by market and by side — the full board is below.
Line Movement
Since Sep 27, 1 PM ET, the moneyline has moved toward Buffalo Bills (New England Patriots price improved from +215 to +275); the spread moved toward Buffalo Bills: Buffalo Bills opened -5.5, now -7; the total dropped from 49.5 to 48.5.
| Market | Tracking opened (Sep 27, 1 PM ET) | Now |
|---|---|---|
| Moneyline (best available) | New England Patriots +215 / Buffalo Bills -244 | New England Patriots +275 / Buffalo Bills -300 |
| Spread (Buffalo Bills, consensus) | -5.5 | -7 (range -7 to -5.5) |
| Total (consensus) | 49.5 | 48.5 |
Full Odds Board
| Sportsbook | New England Patriots | Buffalo Bills | Spread (Buffalo Bills) | Total | O / U |
|---|---|---|---|---|---|
| DraftKings | +245 | -305 | -7 (-105) | 48.5 | -110 / -110 |
| Caesars | +260 | -325 | -7 (-105) | 48.5 | -110 / -110 |
| FanDuel | +265 | -330 | -6.5 (-118) | 48.5 | -110 / -110 |
| ReBet | +238 | -310 | -6.5 (-120) | 48.5 | -110 / -110 |
| BetUS | — | — | -7 (+100) | 48.5 | -110 / -110 |
| LowVig.ag | +245 | -300 | -7 (+105) | 48.5 | -107 / -107 |
| BetOnline.ag | +245 | -300 | -7 (+100) | 48.5 | -110 / -110 |
| BetRivers | +255 | -335 | -7 (-104) | 48.5 | -108 / -113 |
| betPARX | +255 | -335 | -7 (-104) | 48.5 | -108 / -113 |
| Bally Bet | +255 | -335 | -7 (-104) | 48.5 | -108 / -113 |
| MyBookie.ag | +232 | -319 | -7 (-110) | 48.5 | -110 / -110 |
| Fliff | +240 | -335 | -6.5 (-125) | 48.5 | -105 / -115 |
| 888sport | +250 | -333 | -6.5 (-125) | 48.5 | -110 / -110 |
| BetMGM | +275 | -350 | -6.5 (-108) | 48.5 | -110 / -108 |
| theScore Bet | +260 | -320 | -7 (-105) | 48.5 | -110 / -110 |
| Bovada | +255 | -310 | -7 (-105) | 48.5 | -110 / -110 |
| Pinnacle | +250 | -309 | -7 (+100) | 48.5 | -107 / -107 |
| BetAnything | +240 | -300 | -6.5 (-115) | 48.5 | -110 / -110 |
| Hard Rock Bet | +260 | -325 | -6.5 (-115) | 48.5 | -110 / -110 |
Pricing Context: NFL Vig
Lowest-vig sportsbooks for NFL right now: LowVig.ag (B+, 3.18% avg vig), Pinnacle (B+, 3.23% avg vig), BetOnline.ag (B, 4.35% avg vig). Lower vig means the book keeps less of every dollar wagered — the best single-game price and the best long-run pricing are not always the same book. LowVig.ag, which holds a best price on this game, grades B+ on NFL vig overall.
Frequently Asked Questions
Which sportsbook has the best odds for New England Patriots vs Buffalo Bills?
Best available moneyline right now: New England Patriots +275 at BetMGM (runner-up +265 at FanDuel); Buffalo Bills -300 at LowVig.ag (runner-up -300 at BetOnline.ag). Prices refresh hourly — the full board below shows every tracked sportsbook.
What is the spread for New England Patriots vs Buffalo Bills?
The consensus spread is Buffalo Bills -7. Best price at that number: New England Patriots +7 (-110) at MyBookie.ag (runner-up -112 at Pinnacle); Buffalo Bills -7 (+105) at LowVig.ag (runner-up +100 at BetUS). Some sportsbooks deal a different number — the full board below lists every book's spread.
What is the over/under for New England Patriots vs Buffalo Bills?
The consensus total is 48.5. Best price at that number: Over 48.5 (-105) at Fliff (runner-up -107 at LowVig.ag); Under 48.5 (-107) at LowVig.ag (runner-up -107 at Pinnacle).
Has the line moved for New England Patriots vs Buffalo Bills?
Since Sep 27, 1 PM ET, the moneyline has moved toward Buffalo Bills (New England Patriots price improved from +215 to +275); the spread moved toward Buffalo Bills: Buffalo Bills opened -5.5, now -7; the total dropped from 49.5 to 48.5.
How current are these odds?
Odds are refreshed hourly from live sportsbook data (last update: September 28, 2026 at 9:00 AM UTC). Odds change quickly around game time — always verify the price at the book before betting.
How We Calculate These Numbers
- Data Source
- All odds on this page come from The Odds API, which aggregates real-time lines from licensed US and offshore sportsbooks. We track moneyline, spread, and totals markets across every sport with active betting lines.
- Update Frequency
- We pull a fresh snapshot of every tracked market every hour, on the hour (UTC). Each snapshot captures the latest lines from every sportsbook that has posted odds for a given event. The timestamp at the top of each page tells you exactly when the data was last refreshed.
- Vig Calculation
- Vig (short for vigorish, also called juice or overround) measures the margin a sportsbook builds into its odds. We calculate it by converting the odds on each side of a market to implied probabilities, summing those probabilities, and subtracting 100%. For example, a market priced at -110/-110 implies 52.38% on each side — a total of 104.76%, meaning a vig of 4.76%. Lower vig means better value for bettors because you keep more of your winnings.
- Per-Market Breakdown
- We compute vig separately for each market type: moneyline (h2h), point spreads, and totals (over/under). The "average vig" shown for each sportsbook is the mean across all market types weighted by the number of events sampled in each market.
- Grading Scale
- Every sportsbook receives a letter grade based on its average vig: A+ (under 2%) is exchange-level pricing. A (2–3%) is very competitive. B+ (3–4%) is above average. B (4–5%) is the industry standard — a -110/-110 line is 4.76%. C+ (5–6%) is slightly below average. C (6–7%) is below average. D (7–8%) is high vig. D− (8–10%) is very high vig. F (10%+) is predatory pricing. See the full Vig Index Methodology for formulas, worked examples, and known limitations.
- Trend Tracking
- We store daily snapshots for 30 days, allowing us to show 24-hour and 7-day vig trends. A downward trend (improving) means sportsbooks are tightening their lines — often in response to increased competition or higher betting volume as a season heats up.